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Top of web page Study summary Study style Arms and also Interventions Outcome steps Eligibility Criteria Contacts and also Locations an ext Information
Though spit tobacco is smokeless, that still affects the cardiovascular system and also may be associated with heart disease, stroke, and also high blood pressure. Long-term effects of smokeless tobacco (ST) include tooth abrasion, gum recession, mouth disease, lose of bone in the jaw, yellowing of teeth, and chronic bad breath. This research will assess the effectiveness of using tobacco totally free snuff in reducing level of exposure to tobacco and associated toxicity, and also enhancing motivation to one of two people quit or sustain reduced levels of nicotine intake.
condition or disease Intervention/treatment step
Tobacco usage Disorder Drug: Tobacco free snuff step 2

Spit tobacco presents as countless health dangers to its customers as smoking tobacco. Although a far-ranging number that ST users acknowledge the importance of quitting, many either do not desire to battered or feeling it is impossible. For these individuals, tobacco reduction might be an essential transitional goal, either before quitting or together a treatment endpoint. However, approaches to assist ST customers reach this goal have not been studied. This research will evaluate the efficiency of making use of tobacco-free snuff in reducing levels of exposure come tobacco and associated toxicity, and also enhancing an ideas to either quit or sustain lower levels that nicotine intake.

Participants will be randomly assigned to obtain either treatment v tobacco-free snuff or treatment without it. All participants will be encouraged to reduce nicotine input by 50% throughout the an initial four weeks and by 75% the complying with four weeks. Entrants receiving the tobacco-free snuff will certainly be asked to alternative the usage of your usual brand that ST through tobacco-free snuff in bespeak to attain the target reduction. Participants no receiving the tobacco-free snuff will just be informed to try to reduced down their tobacco use to the target reduction. Examine visits will take place once weekly throughout the 8-week therapy period. Assessments will include vital signs, physiological procedures related come tobacco use, and measures of an ideas and self-efficacy come quit ST. The number of participants that either execute not finish treatment, mitigate nicotine intake, or quit fully will be assessed at the main 8 research visit and at follow-up visits, which will certainly be hosted at weeks 12 and 26.


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Layout table for study details
Study kind : Interventional (Clinical Trial)
ActualEnrollment : 138 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: nobody (Open Label)
Primary Purpose: Treatment
Official Title: Treatment the Smokeless Tobacco Users
study Start date : December 2002
Actual primary Completion day : May 2005
Actual study Completion day : May 2005