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SH Lakeland Lab Info
COLLECTION & HANDLINGForms & RequisitionsPatient Home Collection
Please call 616.774.7721 for specimen pick up
GENERAL INFORMATIONOutpatient Draw Sites
GENERAL TEST INFORMATION
Mayo Code: ALS
Epic Code: LAB556
Interface Order Alias: 10078
Former Cerner Code: 8067
Collection Container/Tube: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
1. Centrifuge within 1 hour of collection and aliquot serum intoplastic vial.
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2. Send refrigerated.
Laboratory Test Directory Note:
COLLECTION NOTE: Volumes listed are in serum or plasma, draw approximately 2 1/2 times the requested volume in whole blood.
If not ordering electronically, complete, print, and send aGeneral Request (T239) with the specimen.
Specimen Stability Information
|Serum Red||Refrigerated (preferred)||7 days|
Aldolase is necessary for glycolysis in muscle as a "rapidresponse" pathway for production of adenosine triphosphate,independent of tissue oxygen.
Aldolase catalyzes the conversion of fructose 1,6-diphosphateinto dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, animportant reaction in the glycolytic breakdown of glucose tolactate in muscle.
Aldolase is a tetramer whose primary structure depends upon thetissue from which it was synthesized (highest expression in liver,muscle, brain).
Elevated values are found in muscle diseases, such as Duchennemuscular dystrophy, dermatomyositis, polymyositis, and limb-girdledystrophy. While elevated creatinine kinase (CK) levels are moresensitive and specific for muscle disease, occasionally elevatedaldolase is observed in some patients with myositis that havenormal CK values.
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Test IDTest Order NameOrder LOINC Value
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